Background: The conservation of gene order among prokaryotic genomes can provide valuable insight into gene function, protein interactions, or events by which genomes have evolved...
Christine Fong, Laurence Rohmer, Matthew Radey, Mi...
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...