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122
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AMC
2006
67views more  AMC 2006»
15 years 2 months ago
A general probabilistic model of the PCR process
Earlier work by Saha et al. rigorously derived a general probabilistic model for the PCR process that includes as a special case the Velikanov-Kapral model where all nucleotide re...
Nilanjan Saha, Layne T. Watson, Karen Kafadar, Ale...
BMCBI
2006
92views more  BMCBI 2006»
15 years 2 months ago
Recrafting the neighbor-joining method
Background: The neighbor-joining method by Saitou and Nei is a widely used method for constructing phylogenetic trees. The formulation of the method gives rise to a canonical (n3)...
Thomas Mailund, Gerth Stølting Brodal, Rolf...
108
Voted
BMCBI
2006
108views more  BMCBI 2006»
15 years 2 months ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg
BMCBI
2006
102views more  BMCBI 2006»
15 years 2 months ago
MycoperonDB: a database of computationally identified operons and transcriptional units in Mycobacteria
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Sarita Ranjan, Ranjit Kumar Gundu, Akash Ranjan
BMCBI
2006
136views more  BMCBI 2006»
15 years 2 months ago
Metric for Measuring the Effectiveness of Clustering of DNA Microarray Expression
Background: The recent advancement of microarray technology with lower noise and better affordability makes it possible to determine expression of several thousand genes simultane...
Raja Loganantharaj, Satish Cheepala, John Clifford
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