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114
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ICFP
2010
ACM
15 years 4 months ago
Distance makes the types grow stronger: a calculus for differential privacy
We want assurances that sensitive information will not be disclosed when aggregate data derived from a database is published. Differential privacy offers a strong statistical guar...
Jason Reed, Benjamin C. Pierce
124
Voted
ALMOB
2008
131views more  ALMOB 2008»
15 years 3 months ago
Fast algorithms for computing sequence distances by exhaustive substring composition
The increasing throughput of sequencing raises growing needs for methods of sequence analysis and comparison on a genomic scale, notably, in connection with phylogenetic tree reco...
Alberto Apostolico, Olgert Denas
ALMOB
2007
151views more  ALMOB 2007»
15 years 3 months ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
122
Voted
BMCBI
2010
100views more  BMCBI 2010»
15 years 3 months ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...
155
Voted
BMCBI
2010
189views more  BMCBI 2010»
15 years 3 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
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