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BMCBI
2010
14 years 11 months ago
2010
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
BMCBI
2007
14 years 11 months ago
2007
Background: Since real time PCR was first developed, several approaches to estimating the initial quantity of template in an RT-PCR reaction have been tried. While initially only ...
BMCBI
2007
14 years 11 months ago
2007
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
BMCBI
2007
14 years 11 months ago
2007
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
BMCBI
2007
14 years 11 months ago
2007
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...