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BMCBI
2010
100views more  BMCBI 2010»
14 years 11 months ago
Efficiency clustering for low-density microarrays and its application to QPCR
Background: Pathway-targeted or low-density arrays are used more and more frequently in biomedical research, particularly those arrays that are based on quantitative real-time PCR...
Eric F. Lock, Ryan Ziemiecki, J. S. Marron, Dirk P...
BMCBI
2010
142views more  BMCBI 2010»
14 years 11 months ago
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
Frederick A. Matsen III, Robin B. Kodner, E. Virgi...
BMCBI
2007
103views more  BMCBI 2007»
14 years 11 months ago
Dynamic simulation of regulatory networks using SQUAD
Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
Alessandro Di Cara, Abhishek Garg, Giovanni De Mic...
BMCBI
2007
135views more  BMCBI 2007»
14 years 11 months ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
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BMCBI
2007
146views more  BMCBI 2007»
14 years 11 months ago
PubMed related articles: a probabilistic topic-based model for content similarity
Background: We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document ...
Jimmy J. Lin, W. John Wilbur
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