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BMCBI
2010
113views more  BMCBI 2010»
15 years 2 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
BMCBI
2007
153views more  BMCBI 2007»
15 years 2 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...
118
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BMCBI
2008
123views more  BMCBI 2008»
15 years 2 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
DNIS
2005
Springer
112views Database» more  DNIS 2005»
15 years 8 months ago
Modelling Peer-to-Peer Data Networks Under Complex System Theory
: A Peer-to-peer Data Network (PDN) is an open and evolving society of peer nodes that assemble into a network to share their data for mutual benefit. PDNs are enabled by distribu...
Cyrus Shahabi, Farnoush Banaei Kashani
112
Voted
SIGMOD
1999
ACM
108views Database» more  SIGMOD 1999»
15 years 6 months ago
DynaMat: A Dynamic View Management System for Data Warehouses
Pre-computation and materialization of views with aggregate functions is a common technique in Data Warehouses. Due to the complex structure of the warehouse and the different pro...
Yannis Kotidis, Nick Roussopoulos