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BMCBI
2010
259views more  BMCBI 2010»
14 years 8 months ago
Rule-based spatial modeling with diffusing, geometrically constrained molecules
Background: We suggest a new type of modeling approach for the coarse grained, particle-based spatial simulation of combinatorially complex chemical reaction systems. In our appro...
Gerd Gruenert, Bashar Ibrahim, Thorsten Lenser, Ma...
BMCBI
2010
179views more  BMCBI 2010»
14 years 8 months ago
Circadian signatures in rat liver: from gene expression to pathways
Background: Circadian rhythms are 24 hour oscillations in many behavioural, physiological, cellular and molecular processes that are controlled by an endogenous clock which is ent...
Meric A. Ovacik, Siddharth Sukumaran, Richard R. A...
134
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BMCBI
2011
14 years 8 months ago
Pathway-based analysis using reduced gene subsets in genome-wide association studies
Background: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to s...
Jingyuan Zhao, Simone Gupta, Mark Seielstad, Jianj...
158
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BMCBI
2011
14 years 8 months ago
Logical Development of the Cell Ontology
Background: The Cell Ontology (CL) is an ontology for the representation of in vivo cell types. As biological ontologies such as the CL grow in complexity, they become increasingl...
Terrence F. Meehan, Anna Maria Masci, Amina Abdull...
JMLR
2011
192views more  JMLR 2011»
14 years 8 months ago
Minimum Description Length Penalization for Group and Multi-Task Sparse Learning
We propose a framework MIC (Multiple Inclusion Criterion) for learning sparse models based on the information theoretic Minimum Description Length (MDL) principle. MIC provides an...
Paramveer S. Dhillon, Dean P. Foster, Lyle H. Unga...
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