Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
The computational identification of genes in DNA sequences has become an issue of crucial importance due to the large number of DNA molecules being currently sequenced. We present ...
Background: Array comparative genomic hybridization (CGH) is a technique which detects copy number differences in DNA segments. Complete sequencing of the human genome and the dev...
Bryan Chi, Ronald J. deLeeuw, Bradley P. Coe, Calu...
Many of the same modeling methods used in natural languages, speci cally Markov models and HMM's, have also been applied to biological sequence analysis. In recent years, nat...