We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...
: Phylogenetic profiles of proteins strings of ones and zeros encoding respectively the presence and absence of proteins in a group of genomes have recently been used to id...
Genomes to Life (GTL), the U.S. Department of Energy Office of Science’s systems biology program, focuses on environmental microbiology. Over the next 10 to 20 years, GTL’s ke...
Marvin Frazier, David Thomassen, Aristides Patrino...
Background: We recently developed the Paired End diTag (PET) strategy for efficient characterization of mammalian transcriptomes and genomes. The paired end nature of short PET se...
Kuo Ping Chiu, Chee-Hong Wong, Qiongyu Chen, Prami...
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...