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» Data integration and genomic medicine
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BMCBI
2011
14 years 3 months ago
SeqGene: a comprehensive software solution for mining exome- and transcriptome- sequencing data
Background: The popularity of massively parallel exome and transcriptome sequencing projects demands new data mining tools with a comprehensive set of features to support a wide r...
Xutao Deng
BMCBI
2005
107views more  BMCBI 2005»
14 years 11 months ago
A stepwise framework for the normalization of array CGH data
Background: In two-channel competitive genomic hybridization microarray experiments, the ratio of the two fluorescent signal intensities at each spot on the microarray is commonly...
Mehrnoush Khojasteh, Wan L. Lam, Rabab Kreidieh Wa...
BMCBI
2010
214views more  BMCBI 2010»
14 years 12 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
ICONFERENCE
2011
14 years 6 months ago
Expressing well-being online: towards self-reflection and social awareness
Medicine, psychology and quality of life literature all point to the importance of not just asking ‘how are you?’, but assessing and being aware of self and others’ well-bei...
Paul André, Monica M. C. Schraefel, Alan J....
BMCBI
2010
96views more  BMCBI 2010»
14 years 12 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart