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» Data integration and genomic medicine
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BIB
2007
137views more  BIB 2007»
15 years 2 months ago
Current progress in network research: toward reference networks for key model organisms
The collection of multiple genome-scale datasets is now routine, and the frontier of research in systems biology has shifted accordingly. Rather than clustering a single dataset t...
Balaji S. Srinivasan, Nigam H. Shah, Jason Flannic...
BMCBI
2010
100views more  BMCBI 2010»
15 years 2 months ago
Partitioning of copy-number genotypes in pedigrees
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
Louis-Philippe Lemieux Perreault, Gregor U. Andelf...
BIOINFORMATICS
2005
96views more  BIOINFORMATICS 2005»
15 years 1 months ago
BioLingua: a programmable knowledge environment for biologists
BioLingua is an interactive, web-based programming environment that enables biologists to analyze biological systems by combining knowledge and data through direct end-user progra...
J. P. Massar, Michael Travers, Jeff Elhai, Jeff Sh...
BMCBI
2007
173views more  BMCBI 2007»
15 years 2 months ago
Ringo - an R/Bioconductor package for analyzing ChIP-chip readouts
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is a high-throughput assay for DNA-protein-binding or post-translational chromatin/histone modi...
Joern Toedling, Oleg Sklyar, Tammo Krueger, Jenny ...
BMCBI
2006
122views more  BMCBI 2006»
15 years 1 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen