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BMCBI
2010
114views more  BMCBI 2010»
14 years 9 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BMCBI
2008
173views more  BMCBI 2008»
14 years 9 months ago
Extraction of semantic biomedical relations from text using conditional random fields
Background: The increasing amount of published literature in biomedicine represents an immense source of knowledge, which can only efficiently be accessed by a new generation of a...
Markus Bundschus, Mathäus Dejori, Martin Stet...
BMCBI
2007
172views more  BMCBI 2007»
14 years 9 months ago
msBayes: Pipeline for testing comparative phylogeographic histories using hierarchical approximate Bayesian computation
Background: Although testing for simultaneous divergence (vicariance) across different population-pairs that span the same barrier to gene flow is of central importance to evoluti...
Michael J. Hickerson, Eli Stahl, Naoki Takebayashi
BMCBI
2010
156views more  BMCBI 2010»
14 years 9 months ago
PeakAnalyzer: Genome-wide annotation of chromatin binding and modification loci
Background: Functional genomic studies involving high-throughput sequencing and tiling array applications, such as ChIP-seq and ChIP-chip, generate large numbers of experimentally...
Mali Salmon-Divon, Heidi Dvinge, Kairi Tammoja, Pa...
BMCBI
2010
164views more  BMCBI 2010»
14 years 9 months ago
Investigating the validity of current network analysis on static conglomerate networks by protein network stratification
Background: A molecular network perspective forms the foundation of systems biology. A common practice in analyzing protein-protein interaction (PPI) networks is to perform networ...
Minlu Zhang, Long J. Lu