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GECCO
2008
Springer
129views Optimization» more  GECCO 2008»
15 years 1 months ago
Fitness calculation approach for the switch-case construct in evolutionary testing
A well-designed fitness function is essential to the effectiveness and efficiency of evolutionary testing. Fitness function design has been researched extensively. For fitness ...
Yan Wang, Zhiwen Bai, Miao Zhang, Wen Du, Ying Qin...
114
Voted
BMCBI
2010
148views more  BMCBI 2010»
15 years 18 days ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2010
121views more  BMCBI 2010»
15 years 18 days ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
BMCBI
2007
160views more  BMCBI 2007»
15 years 15 days ago
Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips
Background: Affymetrix GeneChips are a popular platform for performing whole-genome experiments on the transcriptome. There are a range of different calibration steps, and users a...
Andrew P. Harrison, Caroline E. Johnston, Christin...
116
Voted
SISAP
2010
IEEE
135views Data Mining» more  SISAP 2010»
14 years 11 months ago
Improving the similarity search of tandem mass spectra using metric access methods
In biological applications, the tandem mass spectrometry is a widely used method for determining protein and peptide sequences from an ”in vitro” sample. The sequences are not...
Jiri Novák, Tomás Skopal, David Hoks...
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