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BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
15 years 5 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
15 years 5 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
173
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BMCBI
2006
137views more  BMCBI 2006»
15 years 5 months ago
Improving the accuracy of protein secondary structure prediction using structural alignment
Background: The accuracy of protein secondary structure prediction has steadily improved over the past 30 years. Now many secondary structure prediction methods routinely achieve ...
Scott Montgomerie, Shan Sundararaj, Warren J. Gall...
IANDC
2008
128views more  IANDC 2008»
15 years 5 months ago
Rule-based static analysis of network protocol implementations
Today's software systems communicate over the Internet using standard protocols that have been heavily scrutinized, providing some assurance of resistance to malicious attack...
Octavian Udrea, Cristian Lumezanu, Jeffrey S. Fost...
138
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BMCBI
2006
84views more  BMCBI 2006»
15 years 5 months ago
Representation of target-bound drugs by computed conformers: implications for conformational libraries
Background: The increasing number of known protein structures provides valuable information about pharmaceutical targets. Drug binding sites are identifiable and suitable lead com...
Stefan Günther, Christian Senger, Elke Michal...
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