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    BMCBI
    2006
    148views more  BMCBI 2006»
    Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
    14 years 10 months ago
    Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
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    Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
    Jesper Salomon, Darren R. Flower
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    BMCBI
    2006
    113views more  BMCBI 2006»
    QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
    14 years 10 months ago
    QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
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    Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
    Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...
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    BMCBI
    2006
    104views more  BMCBI 2006»
    MANET: tracing evolution of protein architecture in metabolic networks
    14 years 10 months ago
    MANET: tracing evolution of protein architecture in metabolic networks
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    Background: Cellular metabolism can be characterized by networks of enzymatic reactions and transport processes capable of supporting cellular life. Our aim is to find evolutionar...
    Hee Shin Kim, Jay E. Mittenthal, Gustavo Caetano-A...
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    BMCBI
    2006
    133views more  BMCBI 2006»
    An integrated approach to the prediction of domain-domain interactions
    14 years 10 months ago
    An integrated approach to the prediction of domain-domain interactions
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    Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
    Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen
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    BMCBI
    2006
    124views more  BMCBI 2006»
    The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microa
    14 years 10 months ago
    The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microa
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    Background: The Tissue Microarray (TMA) facilitates high-throughput analysis of hundreds of tissue specimens simultaneously. However, bottlenecks in the storage and manipulation o...
    Catherine M. Conway, Deirdre O'Shea, Sallyann O'Br...
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