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BMCBI
2005
14 years 9 months ago
2005
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
BMCBI
2005
14 years 9 months ago
2005
Background: Improvements in technology have been accompanied by the generation of large amounts of complex data. This same technology must be harnessed effectively if the knowledg...
BMCBI
2005
14 years 9 months ago
2005
Background: BLAST is one of the most common and useful tools for Genetic Research. This paper describes a software application we have termed Windows .NET Distributed Basic Local ...
BMCBI
2005
14 years 9 months ago
2005
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
BMCBI
2005
14 years 9 months ago
2005
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...