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» Databases and Algorithms for Pathway Bioinformatics
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CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 2 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
BMCBI
2010
189views more  BMCBI 2010»
14 years 7 months ago
solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Isaak Y. Tecle, Naama Menda, Robert M. Buels, Esth...
BMCBI
2007
165views more  BMCBI 2007»
14 years 9 months ago
Automatic reconstruction of a bacterial regulatory network using Natural Language Processing
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
Carlos Rodríguez Penagos, Heladia Salgado, ...
BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
15 years 2 months ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li
BMCBI
2008
189views more  BMCBI 2008»
14 years 9 months ago
AnEnPi: identification and annotation of analogous enzymes
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
Thomas D. Otto, Ana Carolina R. Guimarães, ...