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» Databases and Algorithms for Pathway Bioinformatics
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BMCBI
2010
155views more  BMCBI 2010»
14 years 9 months ago
A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
BMCBI
2010
153views more  BMCBI 2010»
14 years 9 months ago
GOAL: A software tool for assessing biological significance of genes groups
Background: Modern high throughput experimental techniques such as DNA microarrays often result in large lists of genes. Computational biology tools such as clustering are then us...
Alain B. Tchagang, Alexander Gawronski, Hugo B&eac...
ISBRA
2011
Springer
14 years 28 days ago
Query-Adaptive Ranking with Support Vector Machines for Protein Homology Prediction
Abstract. Protein homology prediction is a crucial step in templatebased protein structure prediction. The functions that rank the proteins in a database according to their homolog...
Yan Fu, Rong Pan, Qiang Yang, Wen Gao
WABI
2009
Springer
124views Bioinformatics» more  WABI 2009»
15 years 4 months ago
Mimosa: Mixture Model of Co-expression to Detect Modulators of Regulatory Interaction
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...
JCB
2007
118views more  JCB 2007»
14 years 9 months ago
Discovering Topological Motifs Using a Compact Notation
Discovering topological motifs or common topologies in one or more graphs is an important as well as an interesting problem. It had been classically viewed as the subgraph isomorp...
Laxmi Parida