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» Databases and Algorithms for Pathway Bioinformatics
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BMCBI
2007
123views more  BMCBI 2007»
14 years 9 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
15 years 4 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
88
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BMCBI
2008
127views more  BMCBI 2008»
14 years 9 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
NAR
2007
216views more  NAR 2007»
14 years 9 months ago
SYSTOMONAS - an integrated database for systems biology analysis of Pseudomonas
To provide an integrated bioinformatics platform for a systems biology approach to the biology of pseudomonads in infection and biotechnology the database SYSTOMONAS (SYSTems biol...
Claudia Choi, Richard Münch, Stefan Leupold, ...
APBC
2003
116views Bioinformatics» more  APBC 2003»
14 years 10 months ago
An Empirical Comparison of Supervised Machine Learning Techniques in Bioinformatics
Research in bioinformatics is driven by the experimental data. Current biological databases are populated by vast amounts of experimental data. Machine learning has been widely ap...
Aik Choon Tan, David Gilbert