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BMCBI
2008
14 years 10 months ago
2008
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
BMCBI
2008
14 years 10 months ago
2008
Background: Analysis of gene expression data for tumor classification is an important application of bioinformatics methods. But it is hard to analyse gene expression data from DN...
BMCBI
2008
14 years 10 months ago
2008
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
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BMCBI
2006
14 years 10 months ago
2006
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
BMCBI
2006
14 years 10 months ago
2006
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...