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BMCBI
2005
127views more  BMCBI 2005»
14 years 9 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
119
Voted
BMCBI
2005
118views more  BMCBI 2005»
14 years 9 months ago
Feature selection and nearest centroid classification for protein mass spectrometry
Background: The use of mass spectrometry as a proteomics tool is poised to revolutionize early disease diagnosis and biomarker identification. Unfortunately, before standard super...
Ilya Levner
BMCBI
2005
93views more  BMCBI 2005»
14 years 9 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
73
Voted
BMCBI
2005
115views more  BMCBI 2005»
14 years 9 months ago
MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays
Background: Enhancements in sequencing technology have recently yielded assemblies of large genomes including rat, mouse, human, fruit fly, and zebrafish. The availability of larg...
Eric C. Rouchka, Abdelnaby Khalyfa, Nigel G. F. Co...
102
Voted
BMCBI
2005
148views more  BMCBI 2005»
14 years 9 months ago
NemaFootPrinter: a web based software for the identification of conserved non-coding genome sequence regions between C. elegans
Background: NemaFootPrinter (Nematode Transcription Factor Scan Through Philogenetic Footprinting) is a web-based software for interactive identification of conserved, non-exonic ...
Davide Rambaldi, Alessandro Guffanti, Paolo Morand...