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BMCBI
2005
152views more  BMCBI 2005»
15 years 2 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
BMCBI
2004
143views more  BMCBI 2004»
15 years 2 months ago
Comparing functional annotation analyses with Catmap
Background: Ranked gene lists from microarray experiments are usually analysed by assigning significance to predefined gene categories, e.g., based on functional annotations. Tool...
Thomas Breslin, Patrik Edén, Morten Krogh
BMCBI
2004
111views more  BMCBI 2004»
15 years 2 months ago
Multiclass discovery in array data
Background: A routine goal in the analysis of microarray data is to identify genes with expression levels that correlate with known classes of experiments. In a growing number of ...
Yingchun Liu, Markus Ringnér
BMCBI
2002
136views more  BMCBI 2002»
15 years 2 months ago
Making sense of EST sequences by CLOBBing them
Background: Expressed sequence tags (ESTs) are single pass reads from randomly selected cDNA clones. They provide a highly cost-effective method to access and identify expressed g...
John Parkinson, David B. Guiliano, Mark L. Blaxter
MICRO
2000
IEEE
176views Hardware» more  MICRO 2000»
15 years 2 months ago
An Advanced Optimizer for the IA-64 Architecture
level of abstraction, compared with the program representation for scalar optimizations. For example, loop unrolling and loop unrolland-jam transformations exploit the large regist...
Rakesh Krishnaiyer, Dattatraya Kulkarni, Daniel M....