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» Derandomization and Distinguishing Complexity
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BMCBI
2006
239views more  BMCBI 2006»
14 years 9 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2006
201views more  BMCBI 2006»
14 years 9 months ago
Gene selection algorithms for microarray data based on least squares support vector machine
Background: In discriminant analysis of microarray data, usually a small number of samples are expressed by a large number of genes. It is not only difficult but also unnecessary ...
E. Ke Tang, Ponnuthurai N. Suganthan, Xin Yao
BMCBI
2006
172views more  BMCBI 2006»
14 years 9 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...
BMCBI
2006
113views more  BMCBI 2006»
14 years 9 months ago
QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...
BMCBI
2007
173views more  BMCBI 2007»
14 years 9 months ago
Recursive Cluster Elimination (RCE) for classification and feature selection from gene expression data
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...