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» Derivation of Characteristic Formulae
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BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
14 years 12 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
BMCBI
2008
107views more  BMCBI 2008»
14 years 12 months ago
A machine learning approach to explore the spectra intensity pattern of peptides using tandem mass spectrometry data
Background: A better understanding of the mechanisms involved in gas-phase fragmentation of peptides is essential for the development of more reliable algorithms for high-throughp...
Cong Zhou, Lucas D. Bowler, Jianfeng Feng
BMCBI
2007
117views more  BMCBI 2007»
14 years 12 months ago
Influence of degree correlations on network structure and stability in protein-protein interaction networks
Background: The existence of negative correlations between degrees of interacting proteins is being discussed since such negative degree correlations were found for the large-scal...
Caroline C. Friedel, Ralf Zimmer
BMCBI
2010
105views more  BMCBI 2010»
14 years 12 months ago
Predicting phenotypic traits of prokaryotes from protein domain frequencies
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
Thomas Lingner, Stefanie Mühlhausen, Toni Gab...
BMCBI
2010
125views more  BMCBI 2010»
14 years 12 months ago
Visualisation tool for peptide fractionation data in proteomics: application to OFFGEL isoelectric focussing
Background: OFFGEL isoelectric focussing (IEF) has become a popular tool in proteomics to fractionate peptides or proteins. As a consequence there is a need for software solutions...
David-Olivier D. Azulay, Hendrik Neubert, Mireia F...