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» Derivation of Characteristic Formulae
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BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
15 years 2 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
115
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BMCBI
2008
107views more  BMCBI 2008»
15 years 2 months ago
A machine learning approach to explore the spectra intensity pattern of peptides using tandem mass spectrometry data
Background: A better understanding of the mechanisms involved in gas-phase fragmentation of peptides is essential for the development of more reliable algorithms for high-throughp...
Cong Zhou, Lucas D. Bowler, Jianfeng Feng
125
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BMCBI
2007
117views more  BMCBI 2007»
15 years 2 months ago
Influence of degree correlations on network structure and stability in protein-protein interaction networks
Background: The existence of negative correlations between degrees of interacting proteins is being discussed since such negative degree correlations were found for the large-scal...
Caroline C. Friedel, Ralf Zimmer
BMCBI
2010
105views more  BMCBI 2010»
15 years 2 months ago
Predicting phenotypic traits of prokaryotes from protein domain frequencies
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
Thomas Lingner, Stefanie Mühlhausen, Toni Gab...
120
Voted
BMCBI
2010
125views more  BMCBI 2010»
15 years 2 months ago
Visualisation tool for peptide fractionation data in proteomics: application to OFFGEL isoelectric focussing
Background: OFFGEL isoelectric focussing (IEF) has become a popular tool in proteomics to fractionate peptides or proteins. As a consequence there is a need for software solutions...
David-Olivier D. Azulay, Hendrik Neubert, Mireia F...