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    BMCBI
    2006
    87views more  BMCBI 2006»
    Prediction of indirect interactions in proteins
    14 years 9 months ago
    Prediction of indirect interactions in proteins
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    Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
    Peteris Prusis, Staffan Uhlén, Ramona Petro...
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    BMCBI
    2006
    152views more  BMCBI 2006»
    A two-stage approach for improved prediction of residue contact maps
    14 years 9 months ago
    A two-stage approach for improved prediction of residue contact maps
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    Background: Protein topology representations such as residue contact maps are an important intermediate step towards ab initio prediction of protein structure. Although improvemen...
    Alessandro Vullo, Ian Walsh, Gianluca Pollastri
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    BMCBI
    2006
    86views more  BMCBI 2006»
    The impact of sample imbalance on identifying differentially expressed genes
    14 years 9 months ago
    The impact of sample imbalance on identifying differentially expressed genes
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    Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
    Kun Yang, Jianzhong Li, Hong Gao
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    BMCBI
    2006
    111views more  BMCBI 2006»
    PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
    14 years 9 months ago
    PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
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    Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
    Tomer Hertz, Chen Yanover
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    BMCBI
    2006
    102views more  BMCBI 2006»
    Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
    14 years 9 months ago
    Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
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    Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
    Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
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