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» Design and modeling of a protein based nanoGripper
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BMCBI
2004
151views more  BMCBI 2004»
14 years 9 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2010
141views more  BMCBI 2010»
14 years 10 months ago
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Franziska Hoffgaard, Philipp Weil, Kay Hamacher
COMAD
2008
14 years 11 months ago
REBMEC: Repeat Based Maximum Entropy Classifier for Biological Sequences
An important problem in biological data analysis is to predict the family of a newly discovered sequence like a protein or DNA sequence, using the collection of available sequence...
Pratibha Rani, Vikram Pudi
ISMB
1996
14 years 11 months ago
Refining Neural Network Predictions for Helical Transmembrane Proteins by Dynamic Programming
For transmembrane proteins experimental determina-tion of three-dimensional structure is problematic. However, membrane proteins have important impact for molecular biology in gen...
Burkhard Rost, Rita Casadio, Piero Fariselli