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» Design and modeling of a protein based nanoGripper
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BIOINFORMATICS
2007
151views more  BIOINFORMATICS 2007»
14 years 10 months ago
A new protein-protein docking scoring function based on interface residue properties
Motivation: Protein–protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low s...
Julie Bernauer, Jérôme Azé, Jo...
GECCO
2007
Springer
154views Optimization» more  GECCO 2007»
15 years 4 months ago
A novel ab-initio genetic-based approach for protein folding prediction
In this paper, a model based on genetic algorithms for protein folding prediction is proposed. The most important features of the proposed approach are: i) Heuristic secondary str...
Sergio Raul Duarte Torres, David Camilo Becerra Ro...
BMCBI
2008
163views more  BMCBI 2008»
14 years 10 months ago
Nuclear staining and relative distance for quantifying epidermal differentiation in biomarker expression profiling
Background: The epidermal physiology results from a complex regulated homeostasis of keratinocyte proliferation, differentiation and death and is tightly regulated by a specific p...
Thora Pommerencke, Thorsten Steinberg, Hartmut Dic...
ISBI
2009
IEEE
15 years 4 months ago
Instance-Based Generative Biological Shape Modeling
Biological shape modeling is an essential task that is required for systems biology efforts to simulate complex cell behaviors. Statistical learning methods have been used to buil...
Tao Peng, Wei Wang, Gustavo K. Rohde, Robert F. Mu...
JCB
2007
144views more  JCB 2007»
14 years 9 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...