We present an optimization method and algorithm designed for three objectives: physical data independence, semantic optimization, and generalized tableau minimization. The method ...
Background: Microarray devices permit a genome-scale evaluation of gene function. This technology has catalyzed biomedical research and development in recent years. As many import...
While there have been intensive efforts in developing better 3D flow visualization techniques, little attention has been paid to the design of better user interfaces and more effe...
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...