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» Designing Nucleotide Sequences for Computation: A Survey of ...
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SAC
2010
ACM
14 years 10 months ago
FANGS: high speed sequence mapping for next generation sequencers
Next Generation Sequencing machines are generating millions of short DNA sequences (reads) everyday. There is a need for efficient algorithms to map these sequences to the referen...
Sanchit Misra, Ramanathan Narayanan, Simon Lin, Al...
CCECE
2006
IEEE
15 years 3 months ago
Survey of Biological High Performance Computing: Algorithms, Implementations and Outlook Research
During recent years there has been an explosive growth of biological data coming from genome projects, proteomics, protein structure determination, and the rapid expansion in digi...
Nasreddine Hireche, J. M. Pierre Langlois, Gabriel...
BMCBI
2007
153views more  BMCBI 2007»
14 years 10 months ago
Can Clustal-style progressive pairwise alignment of multiple sequences be used in RNA secondary structure prediction?
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
Amelia B. Bellamy-Royds, Marcel Turcotte
ISMB
1997
14 years 11 months ago
SEALS: A System for Easy Analysis of Lots of Sequences
We present a system of programs designed to facilitate sequence analysis projects involving large amounts of data. SEALS (System for Easy Analysis of Lots of Sequences) is a logic...
D. Roland Walker, Eugene V. Koonin
BMCBI
2006
123views more  BMCBI 2006»
14 years 9 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...