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121
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BMCBI
2005
15 years 3 months ago
2005
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
118
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BMCBI
2005
15 years 3 months ago
2005
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
130
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BMCBI
2005
15 years 3 months ago
2005
Background: The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has ...
166
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BMCBI
2005
15 years 3 months ago
2005
Background: Complete sequencing of bacterial genomes has become a common technique of present day microbiology. Thereafter, data mining in the complete sequence is an essential st...
138
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BMCBI
2004
15 years 3 months ago
2004
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...