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BMCBI
2010
140views more  BMCBI 2010»
14 years 12 months ago
Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection
Background: Liquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is on...
Tianwei Yu, Hesen Peng
BMCBI
2007
127views more  BMCBI 2007»
14 years 12 months ago
The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments
Background: Isotope-coded affinity tags (ICAT) is a method for quantitative proteomics based on differential isotopic labeling, sample digestion and mass spectrometry (MS). The me...
Mario Cannataro, Giovanni Cuda, Marco Gaspari, Ser...
BMCBI
2007
93views more  BMCBI 2007»
14 years 12 months ago
Representing default knowledge in biomedical ontologies: application to the integration of anatomy and phenotype ontologies
Background: Current efforts within the biomedical ontology community focus on achieving interoperability between various biomedical ontologies that cover a range of diverse domain...
Robert Hoehndorf, Frank Loebe, Janet Kelso, Heinri...
BMCBI
2010
105views more  BMCBI 2010»
14 years 12 months ago
The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems
Background: The Gene Ontology (GO) is used to describe genes and gene products from many organisms. When used for functional annotation of microarray data, GO is often slimmed by ...
Nophar Geifman, Alon Monsonego, Eitan Rubin
BMCBI
2008
111views more  BMCBI 2008»
14 years 12 months ago
SimHap GUI: An intuitive graphical user interface for genetic association analysis
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
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