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BMCBI
2005
135views more  BMCBI 2005»
14 years 10 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
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BMCBI
2005
104views more  BMCBI 2005»
14 years 10 months ago
An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer i
Background: Neoplastic transformation is a multistep process in which distinct gene products of specific cell regulatory pathways are involved at each stage. Identification of ove...
Federica Cavallo, Annalisa Astolfi, Manuela Iezzi,...
JCB
2007
144views more  JCB 2007»
14 years 10 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
BMCBI
2005
87views more  BMCBI 2005»
14 years 10 months ago
BioCreAtIvE Task 1A: gene mention finding evaluation
Background: The biological research literature is a major repository of knowledge. As the amount of literature increases, it will get harder to find the information of interest on...
Alexander S. Yeh, Alexander A. Morgan, Marc E. Col...
BMCBI
2005
157views more  BMCBI 2005»
14 years 10 months ago
Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...
Qian Xie, Luke D. Ratnasinghe, Huixiao Hong, Roger...
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