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BMCBI
2010
179views more  BMCBI 2010»
15 years 22 days ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
96
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BMCBI
2010
111views more  BMCBI 2010»
15 years 22 days ago
Protein sequences classification by means of feature extraction with substitution matrices
Background: This paper deals with the preprocessing of protein sequences for supervised classification. Motif extraction is one way to address that task. It has been largely used ...
Rabie Saidi, Mondher Maddouri, Engelbert Mephu Ngu...
87
Voted
BMCBI
2010
125views more  BMCBI 2010»
15 years 22 days ago
NeatMap - non-clustering heat map alternatives in R
Background: The clustered heat map is the most popular means of visualizing genomic data. It compactly displays a large amount of data in an intuitive format that facilitates the ...
Satwik Rajaram, Yoshi Oono
94
Voted
BMCBI
2010
108views more  BMCBI 2010»
15 years 22 days ago
Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
99
Voted
BMCBI
2010
156views more  BMCBI 2010»
15 years 22 days ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
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