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» Detecting Motifs from Sequences
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ISAAC
2004
Springer
115views Algorithms» more  ISAAC 2004»
15 years 3 months ago
Randomized Algorithms for Motif Detection
Motivation: Motif detection for DNA sequences has many important applications in biological studies, e.g., locating binding sites and regulatory signals, and designing genetic prob...
Lusheng Wang, Liang Dong, Hui Fan
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Discriminative Discovery of Transcription Factor Binding Sites from Location Data
Motivation: The availability of genome-wide location analyses based on chromatin immunoprecipitation (ChIP) data gives a new insight for in silico analysis of transcriptional regu...
Yuji Kawada, Yasubumi Sakakibara
72
Voted
BMCBI
2007
125views more  BMCBI 2007»
14 years 9 months ago
Statistical tests to compare motif count exceptionalities
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...
Stéphane Robin, Sophie Schbath, Vincent Van...
RECOMB
2002
Springer
15 years 10 months ago
Finding motifs in the twilight zone
We introduce the notion of a multiprofile and use it for finding subtle motifs in DNA sequences. Multiprofiles generalize the notion of a profile and allow one to detect subtle co...
Uri Keich, Pavel A. Pevzner
80
Voted
BMCBI
2006
112views more  BMCBI 2006»
14 years 9 months ago
A correlated motif approach for finding short linear motifs from protein interaction networks
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...