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BMCBI
2008
143views more  BMCBI 2008»
14 years 10 months ago
catmap: Case-control And TDT Meta-Analysis Package
Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...
Kristin K. Nicodemus
CN
2008
128views more  CN 2008»
14 years 9 months ago
Autonomous security for autonomous systems
The Internet's interdomain routing protocol, BGP, supports a complex network of Autonomous Systems which is vulnerable to a number of potentially crippling attacks. Several p...
Josh Karlin, Stephanie Forrest, Jennifer Rexford
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BMCBI
2006
85views more  BMCBI 2006»
14 years 9 months ago
Identification of physicochemical selective pressure on protein encoding nucleotide sequences
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
BMCBI
2006
132views more  BMCBI 2006»
14 years 9 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas
BMCBI
2007
116views more  BMCBI 2007»
14 years 9 months ago
Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases
Background: The pyridine nucleotide disulfide reductase (PNDR) is a large and heterogeneous protein family divided into two classes (I and II), which reflect the divergent evoluti...
César L. Avila, Viviana A. Rapisarda, Ricar...