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» Detecting microRNA activity from gene expression data
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BMCBI
2010
216views more  BMCBI 2010»
14 years 7 months ago
Bayesian Inference of the Number of Factors in Gene-Expression Analysis: Application to Human Virus Challenge Studies
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
Bo Chen, Minhua Chen, John William Paisley, Aimee ...
BMCBI
2006
96views more  BMCBI 2006»
15 years 17 days ago
Bayesian detection of periodic mRNA time profiles without use of training examples
Background: Detection of periodically expressed genes from microarray data without use of known periodic and non-periodic training examples is an important problem, e.g. for ident...
Claes R. Andersson, Anders Isaksson, Mats G. Gusta...
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BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
15 years 17 days ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
SAC
2004
ACM
15 years 6 months ago
Time-frequency feature detection for time-course microarray data
Gene clustering based on microarray data provides useful functional information to the working biologists. Many current gene-clustering algorithms rely on Euclidean-based distance...
Jiawu Feng, Paolo Emilio Barbano, Bud Mishra
BMCBI
2004
146views more  BMCBI 2004»
15 years 11 days ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker