High throughput expression profiling and genotyping technologies provide the means to study the genetic determinants of population variation in gene expression variation. In this ...
Computing reliable gene expression levels from microarray experiments is a sophisticated process with many potential pitfalls. Quality control is one of the most important steps i...
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
Background: Novel strategies are required in order to handle the huge amount of data produced by microarray technologies. To infer gene regulatory networks, the first step is to f...
Background: Various statistical scores have been proposed for evaluating the significance of genes that may exhibit differential expression between two or more controlled conditio...