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» Detecting microRNA activity from gene expression data
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BMCBI
2010
135views more  BMCBI 2010»
14 years 10 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
91
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BMCBI
2008
126views more  BMCBI 2008»
14 years 10 months ago
Methods for evaluating gene expression from Affymetrix microarray datasets
Background: Affymetrix high density oligonucleotide expression arrays are widely used across all fields of biological research for measuring genome-wide gene expression. An import...
Ning Jiang, Lindsey J. Leach, Xiaohua Hu, Elena Po...
BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...
NAR
2011
340views Computer Vision» more  NAR 2011»
14 years 28 days ago
CCDB: a curated database of genes involved in cervix cancer
The Cervical Cancer gene DataBase (CCDB, http:// crdd.osdd.net/raghava/ccdb) is a manually curated catalog of experimentally validated genes that are thought, or are known to be i...
Subhash M. Agarwal, Dhwani Raghav, Harinder Singh,...
BMCBI
2011
14 years 1 months ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson