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» Determining Consensus Numbers
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BMCBI
2010
205views more  BMCBI 2010»
15 years 26 days ago
A fast indexing approach for protein structure comparison
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
Lei Zhang, James Bailey, Arun Siddharth Konagurthu...
BMCBI
2007
127views more  BMCBI 2007»
15 years 26 days ago
Characterization of protein-interaction networks in tumors
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
Alexander Platzer, Paul Perco, Arno Lukas, Bernd M...
120
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BMCBI
2010
165views more  BMCBI 2010»
15 years 26 days ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
96
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BMCBI
2007
97views more  BMCBI 2007»
15 years 26 days ago
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
CORR
2010
Springer
209views Education» more  CORR 2010»
15 years 25 days ago
An Algorithm to Extract Rules from Artificial Neural Networks for Medical Diagnosis Problems
Artificial neural networks (ANNs) have been successfully applied to solve a variety of classification and function approximation problems. Although ANNs can generally predict bett...
S. M. Kamruzzaman, Md. Monirul Islam