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BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
WSDM
2012
ACM
301views Data Mining» more  WSDM 2012»
12 years 1 months ago
Learning evolving and emerging topics in social media: a dynamic nmf approach with temporal regularization
As massive repositories of real-time human commentary, social media platforms have arguably evolved far beyond passive facilitation of online social interactions. Rapid analysis o...
Ankan Saha, Vikas Sindhwani
BMCBI
2007
156views more  BMCBI 2007»
13 years 6 months ago
Predictive modeling of plant messenger RNA polyadenylation sites
Background: One of the essential processing events during pre-mRNA maturation is the posttranscriptional addition of a polyadenine [poly(A)] tail. The 3'-end poly(A) track pr...
Guoli Ji, Jianti Zheng, Yingjia Shen, Xiaohui Wu, ...
BMCBI
2010
121views more  BMCBI 2010»
13 years 6 months ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen
BMCBI
2007
111views more  BMCBI 2007»
13 years 6 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda