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BMCBI
2007
109views more  BMCBI 2007»
15 years 25 days ago
A domain-based approach to predict protein-protein interactions
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Mudita Singhal, Haluk Resat
130
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BMCBI
2008
131views more  BMCBI 2008»
15 years 25 days ago
Major copy proportion analysis of tumor samples using SNP arrays
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
Cheng Li, Rameen Beroukhim, Barbara A. Weir, Wendy...
96
Voted
BMCBI
2007
86views more  BMCBI 2007»
15 years 25 days ago
Detecting microsatellites within genomes: significant variation among algorithms
Background: Microsatellites are short, tandemly-repeated DNA sequences which are widely distributed among genomes. Their structure, role and evolution can be analyzed based on exh...
Sébastien Leclercq, Eric Rivals, Philippe J...
119
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BMCBI
2008
135views more  BMCBI 2008»
15 years 25 days ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BMCBI
2010
135views more  BMCBI 2010»
15 years 25 days ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
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