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83
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BMCBI
2007
131views more  BMCBI 2007»
15 years 25 days ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
95
Voted
BMCBI
2008
179views more  BMCBI 2008»
15 years 25 days ago
Bayesian modeling of recombination events in bacterial populations
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fa...
Pekka Marttinen, Adam Baldwin, William P. Hanage, ...
BMCBI
2008
100views more  BMCBI 2008»
15 years 25 days ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
94
Voted
BMCBI
2008
128views more  BMCBI 2008»
15 years 25 days ago
An efficient visualization tool for the analysis of protein mutation matrices
Background: It is useful to develop a tool that would effectively describe protein mutation matrices specifically geared towards the identification of mutations that produce eithe...
Maria Pamela C. David, Carlo M. Lapid, Vincent Ric...
105
Voted
BMCBI
2008
150views more  BMCBI 2008»
15 years 25 days ago
13C labeling experiments at metabolic nonstationary conditions: An exploratory study
Background: Stimulus Response Experiments to unravel the regulatory properties of metabolic networks are becoming more and more popular. However, their ability to determine enzyme...
Sebastian Aljoscha Wahl, Katharina Nöh, Wolfg...
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