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BMCBI
2010
110views more  BMCBI 2010»
14 years 12 months ago
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2007
88views more  BMCBI 2007»
14 years 12 months ago
Computational analysis of the relationship between allergenicity and digestibility of allergenic proteins in simulated gastric f
Background: Safety assessment of genetically modified (GM) food, with regard to allergenic potential of transgene-encoded xenoproteins, typically involves several different method...
Bingjun Jiang, Hong Qu, Yuanlei Hu, Ting Ni, Zhong...
BMCBI
2008
133views more  BMCBI 2008»
14 years 12 months ago
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...
BMCBI
2008
78views more  BMCBI 2008»
14 years 12 months ago
A new protein linear motif benchmark for multiple sequence alignment software
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
Emmanuel Perrodou, Claudia Chica, Olivier Poch, To...
BMCBI
2010
124views more  BMCBI 2010»
14 years 12 months ago
GPFrontend and GPGraphics: graphical analysis tools for genetic association studies
Background: Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. ...
Steffen Uebe, Francesca Pasutto, Mandy Krumbiegel,...
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