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BMCBI
2010
118views more  BMCBI 2010»
15 years 5 months ago
From learning taxonomies to phylogenetic learning: Integration of 16S rRNA gene data into FAME-based bacterial classification
Background: Machine learning techniques have shown to improve bacterial species classification based on fatty acid methyl ester (FAME) data. Nonetheless, FAME analysis has a limit...
Bram Slabbinck, Willem Waegeman, Peter Dawyndt, Pa...
BMCBI
2008
141views more  BMCBI 2008»
15 years 5 months ago
Discovering functional interaction patterns in protein-protein interaction networks
Background: In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of ge...
Mehmet E. Turanalp, Tolga Can
BMCBI
2007
146views more  BMCBI 2007»
15 years 5 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2008
100views more  BMCBI 2008»
15 years 5 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
DEBU
2008
186views more  DEBU 2008»
15 years 5 months ago
A Survey of Collaborative Recommendation and the Robustness of Model-Based Algorithms
The open nature of collaborative recommender systems allows attackers who inject biased profile data to have a significant impact on the recommendations produced. Standard memory-...
Jeff J. Sandvig, Bamshad Mobasher, Robin D. Burke