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BMCBI
2010
86views more  BMCBI 2010»
15 years 22 hour ago
Protein binding hot spots and the residue-residue pairing preference: a water exclusion perspective
Background: A protein binding hot spot is a small cluster of residues tightly packed at the center of the interface between two interacting proteins. Though a hot spot constitutes...
Qian Liu, Jinyan Li
BMCBI
2008
121views more  BMCBI 2008»
15 years 19 hour ago
Modularization of biochemical networks based on classification of Petri net t-invariants
Background: Structural analysis of biochemical networks is a growing field in bioinformatics and systems biology. The availability of an increasing amount of biological data from ...
Eva Grafahrend-Belau, Falk Schreiber, Monika Heine...
BMCBI
2006
92views more  BMCBI 2006»
14 years 12 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
BMCBI
2006
127views more  BMCBI 2006»
14 years 12 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
DATAMINE
2006
176views more  DATAMINE 2006»
14 years 12 months ago
A Bit Level Representation for Time Series Data Mining with Shape Based Similarity
Clipping is the process of transforming a real valued series into a sequence of bits representing whether each data is above or below the average. In this paper, we argue that clip...
Anthony J. Bagnall, Chotirat (Ann) Ratanamahatana,...