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» Differential Power Analysis Model and Some Results
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BMCBI
2010
80views more  BMCBI 2010»
14 years 12 months ago
Power and sample size estimation in microarray studies
Background: Before conducting a microarray experiment, one important issue that needs to be determined is the number of arrays required in order to have adequate power to identify...
Wei-Jiun Lin, Huey-miin Hsueh, James J. Chen
BMCBI
2004
180views more  BMCBI 2004»
14 years 11 months ago
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovaria
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
BMCBI
2007
135views more  BMCBI 2007»
14 years 12 months ago
Detecting multivariate differentially expressed genes
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
Roland Nilsson, José M. Peña, Johan ...
BMCBI
2008
110views more  BMCBI 2008»
14 years 12 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
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ISBI
2011
IEEE
14 years 3 months ago
Automatic mask generation using independent component analysis in dynamic contrast enhanced-MRI
Studying image intensity change in each pixel in dynamic contrast enhanced (DCE)-MRI data enables differentiation of different tissue types based on their difference in contrast u...
Hatef Mehrabian, Ian Pang, Chaitanya Chandrana, Ra...