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» Dimensionality Reduction for Classification
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BMCBI
2005
112views more  BMCBI 2005»
15 years 3 months ago
Towards precise classification of cancers based on robust gene functional expression profiles
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Zheng Guo, Tianwen Zhang, Xia Li, Qi Wang, Jianzhe...
BIBE
2001
IEEE
15 years 7 months ago
Gene Classification using Expression Profiles: A Feasibility Study
As various genome sequencing projects have already been completed or are near completion, genome researchers are shifting their focus from structural genomics to functional genomi...
Michihiro Kuramochi, George Karypis
NIPS
1997
15 years 4 months ago
EM Algorithms for PCA and SPCA
I present an expectation-maximization (EM) algorithm for principal component analysis (PCA). The algorithm allows a few eigenvectors and eigenvalues to be extracted from large col...
Sam T. Roweis
BMCBI
2008
175views more  BMCBI 2008»
15 years 3 months ago
Comprehensive inventory of protein complexes in the Protein Data Bank from consistent classification of interfaces
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
Andrew J. Bordner, Andrey A. Gorin
ISBI
2008
IEEE
16 years 4 months ago
Support vector machine for data on manifolds: An application to image analysis
The Support Vector Machine (SVM) is a powerful tool for classification. We generalize SVM to work with data objects that are naturally understood to be lying on curved manifolds, ...
Suman K. Sen, Mark Foskey, James Stephen Marron, M...