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ECCB
2005
IEEE
15 years 3 months ago
A query language for biological networks
Many areas of modern biology are concerned with the management, storage, visualization, comparison, and analysis of networks. For instance, networks are used to model signal trans...
Ulf Leser
BMCBI
2007
133views more  BMCBI 2007»
14 years 10 months ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
BMCBI
2008
153views more  BMCBI 2008»
14 years 10 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani
BMCBI
2007
157views more  BMCBI 2007»
14 years 10 months ago
A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellula
Background: The fundamental role that intrinsic stochasticity plays in cellular functions has been shown via numerous computational and experimental studies. In the face of such e...
Asawari Samant, Babatunde A. Ogunnaike, Dionisios ...
BMCBI
2010
83views more  BMCBI 2010»
14 years 10 months ago
Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteins
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
William P. Kelly, Michael P. H. Stumpf