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BMCBI
2006
130views more  BMCBI 2006»
14 years 11 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
CAD
2006
Springer
14 years 11 months ago
A unified subdivision approach for multi-dimensional non-manifold modeling
This paper presents a new unified subdivision scheme that is defined over a k-simplicial complex in n-D space with k 3. We first present a series of definitions to facilitate top...
Yu-Sung Chang, Hong Qin
BMCBI
2007
147views more  BMCBI 2007»
14 years 11 months ago
Modeling biochemical transformation processes and information processing with Narrator
Background: Software tools that model and simulate the dynamics of biological processes and systems are becoming increasingly important. Some of these tools offer sophisticated gr...
Johannes J. Mandel, Hendrik Fuß, Niall M. Pa...
BMCBI
2007
110views more  BMCBI 2007»
14 years 11 months ago
Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy
Background: The design of long oligonucleotides for spotted DNA microarrays requires detailed attention to ensure their optimal performance in the hybridization process. The main ...
Guangan Hu, Manuel Llinás, Jingguang Li, Pe...
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BMCBI
2007
113views more  BMCBI 2007»
14 years 11 months ago
Statistical tools for transgene copy number estimation based on real-time PCR
Background: As compared with traditional transgene copy number detection technologies such as Southern blot analysis, real-time PCR provides a fast, inexpensive and high-throughpu...
Joshua S. Yuan, Jason N. Burris, Nathan R. Stewart...