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ICFP
2010
ACM
15 years 5 months ago
The impact of higher-order state and control effects on local relational reasoning
Reasoning about program equivalence is one of the oldest problems in semantics. In recent years, useful techniques have been developed, based on bisimulations and logical relation...
Derek Dreyer, Georg Neis, Lars Birkedal
BMCBI
2010
130views more  BMCBI 2010»
15 years 4 months ago
The behaviour of random forest permutation-based variable importance measures under predictor correlation
Background: Random forests (RF) have been increasingly used in applications such as genome-wide association and microarray studies where predictor correlation is frequently observ...
Kristin K. Nicodemus, James D. Malley, Carolin Str...
BMCBI
2010
86views more  BMCBI 2010»
15 years 4 months ago
A novel approach to simulate gene-environment interactions in complex diseases
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with lar...
Roberto Amato, Michele Pinelli, Daniel D'Andrea, G...
BMCBI
2010
151views more  BMCBI 2010»
15 years 4 months ago
Data reduction for spectral clustering to analyze high throughput flow cytometry data
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...
BMCBI
2008
242views more  BMCBI 2008»
15 years 4 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...